FACULTY PROFILE

Dr. Samiran Mondal

  • Assistant Professor(Stage-II)

  • Department of Chemistry

  • M.Sc, Ph.D, MRSC

  • This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.

 

  • Research interest
    The motivation of our research group is to understand the molecular basis of biological phenomena using fluorescence spectroscopy. By utilizing the prior background in fluorochemistry, nano-science, and molecular biology, our research group has extensively explored the fields in a biological context specifically in the field of small-molecule drug discovery. Our research interests mainly focus on the following fields:
    • Modulation of protein-protein interaction with small molecules particularly relevant to the discovery of novel therapeutic agents for cancer therapies.
    • Chemical approaches to modulating innate immunity or activating energy metabolism of T cells with the goal of providing reagents useful for cancer immunotherapy.
    • Studying the mechanism of amyloid aggregation related to Diabetes, Alzheimer's disease, and other neurodegenerative diseases.
    • Development of naturally occurring small molecules and their synthetic analogs with potential antiviral efficiency.

  • Title of the Thesis
    “Photophysical studies on some biologically relevant chromophores and development of biogenic synthetic methods for metal nanoparticles”.

  • Project
    ◉ Modulating protein-protein interactions by small molecules: A quest for novel cancer theranostics, Memo No. 1352(Sanc.)/STBT-11012(25)/46/2021-ST SEC, funded by Science & Technology and Biotechnology, Govt. of West Bengal [2022-2025], Principal Investigator.
    ◉ Search for a regulatory mechanism of biflavone based SARS-CoV-2 main protease inhibition and immune modulation, RSC Research Fund Grant (R21-3846200522), funded by The Royal Society of Chemistry, UK [2022-2023], Principal Investigator.
    ◉ Unfolding the role of small molecule based fluorescent antioxidants towards the misfolding of amyloid proteins: A study to detect and inhibit amyloid aggregations, Memo No. 1934(Sanc.)/ST/P/S&T/15G-20/2019, funded by Science & Technology and Biotechnology, Govt. of West Bengal [2020-2023], Co-Principal Investigator.
    ◉ Fluorescence spectroscopy for investigating biochemical events in small molecular length scales, Memo No. F.PSW-112/15-16 (ERO) dated 16/11/2016, funded by University Grants Commission (UGC) [2016-2018], Principal Investigator.

  • Visit my Google Scholar Profile

  • ORCID iD iconhttps://orcid.org/0000-0003-4455-1202

                 

  • Research guidance
    ◉ One Junior Research fellow (JRF) [Mr. Suvankar Karmakar] has joined in the WB-DSTBT, Government of West Bengal, funded R&D project entitled “Modulating protein-protein interactions by small molecules: A quest for novel cancer theranostics” sanctioned Memo No. 1352(Sanc.)/STBT-11012(25)/46/2021-ST SEC dated 21.03.2022, under the supervision of Dr. Samiran Mondal, Assistant Professor & Principal Investigator, Department of Chemistry.

                 

  • Research publications
    22

  •  Fellowships/Awards/Honours/Achievements

    ● Indian Chemical Society Research Excellence Award, International Seminar on Recent Advances in Chemistry & Material Sciences 2020, Indian Chemical Society & American Chemical Society (2020).
    ● Outstanding Paper Award, 3rd Regional Science and Technology Congress, DST, Govt. of West Bengal, West Bengal, India (2018).
    ● International Travel Grant, SERB, Department of Science and Technology (DST), Govt. of India (2017).
    ● Outstanding Paper Award, 1st Regional Science and Technology Congress, DST, Govt. of West Bengal, West Bengal, India (2016).
    ● Jeffrey Modell foundation Best Abstract Award, Frontiers in Immunology conference, Nobel Forum, Stockholm, Sweden (2014).
    ● Young Scientists Award, 63rd Lindau Nobel Laureate Meeting (Chemistry), Council for the Lindau Nobel Laureate Meeting, Germany (2013).
    ● Awarded HFSP-CDF Postdoctoral fellowship, International Human Frontier Science Program Organization, France (2012).
    ●Young Researcher and Third Prize in Poster, ICONSAT, Hyderabad, India (2012).
    ● Best Poster Award, 13th CRSI National Symposium, NISER, Bhubaneswar, India (2011).
    ● One of the Best 10 Posters Award, 3rd APSRC & 10th TSRP, BARC, India (2010).
    ● Second Prize in Poster, ICN, Mahatma Gandhi University, India (2010).
    ●Junior Research Fellow (Chemical Sciences) in JOINT CSIR-UGC NET (National Eligibility Test), Govt. of India (2008).     

     

 

    • S. Mondal*, A. Karmakar, T. Mallick, N.A. Begum, “Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion”, Virology, 2021, 556, 133-139. [https://doi.org/10.1016/j.virol.2021.01.015], [IF: 3.616].

    • A. Karmakar, T. Mallick, C. Fouzder, A. Mukhuty, S. Mondal, R. Kundu, N. A. Begum*, Understanding the Role of Flavonoid Based Small Molecules in Modulating the Oncogenic Protein-Protein Interactions: A Quest for Therapeutic Arsenal, J. Mol. Struct., 2022, 1248, 131511. [https://doi.org/10.1016/j.molstruc.2021.131511], [IF: 3.196].

    •  N. A. Begum, F. Haque, A. Stanlie, A. Husain, S. Mondal, M. Nakata, T. Taniguchi, H. Taniguchi, T. Honjo*, “Non-canonical role of Phf5a in DNA repair and antibody class switch recombination relies on histone H2A variants regulation”, EMBO J., 2021, 40, e106393. [https://doi.org/10.15252/embj.2020106393], [IF: 11.6].
    •  T. Mallick, A. Karmakar, A. Mukhuty, C. Fouzder, J. Mandal, S. Mondal, A. Pramanik, R. Kundu, N. A. Begum*, “Exploring the Propensities of Fluorescent Carbazole Analogs toward the Inhibition of Amyloid Aggregation in Type 2 Diabetes: An Experimental and Theoretical Endeavor”, Journal of Physical Chemistry B,., 2021, 125, 10481-10493.[https://doi.org/10.1021/acs.jpcb.1c06161], [IF: 2.991].
    •  A. Karmakar, T. Mallick, C. Fouzder, A. Mukhuty, S. Mondal, A. Pramanik, R. Kundu, D. Mandal , S. Das, N.A. Begum*, “Unfolding the Role of a Flavone-Based Fluorescent Antioxidant towards the Misfolding of Amyloid Proteins: An Endeavour to Probe Amyloid Aggregation”, Journal of Physical Chemistry B,., 2020, 124, 49, 11133-11144.[https://doi.org/10.1021/acs.jpcb.0c08729], [IF: 2.991]
    •  D. Kumari, T. Mallick, A. Karmakar, S. Mondal, S. Das, N.A. Begum*, “Curry leaf and its antioxidant potential: A systematic study to enhance its activity in aqueous medium”, Current Nutrition & Food Science, 2020, 16, 323. [https://doi.org/10.2174/1573401314666181002142757], [IF: 0.92].
    • D. Kumari, T. Mallick, P. Padhy, S. Mondal*, A. Karmakar*, N.A. Begum*, “Degradation of toxic organic dyes in aqueous medium in greener ways: Exploring the utility of Indian Curry Leaf plant and the nanoparticles synthesized by it”, Desalination & Water Treatment, 2018, 129, 266. [https://doi.org/10.5004/dwt.2018.23078], [IF: 1.234].
    • S. Mondal, N. A. Begum, W. Hu, T. Honjo*, “Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins”, Proceedings of the National Academy of Sciences (PNAS), 2016, 113, E1545. [https://doi.org/10.1073/pnas.1601678113], [IF: 11.2]. 
    • W. Hu, N. A. Begum, S. Mondal, A. Stanlie, T. Honjo*, “Identification of DNA cleavage- and recombination-specific hnRNP co-factors for Activation-induced cytidine deaminase”, Proceedings of the National Academy of Sciences (PNAS), 2015, 112, 5791. [https://doi.org/10.1073/pnas.1506167112], [IF: 11.2].
    • A. S. Yousif, A. Stanlie, S. Mondal, T. Honjo*, N. A. Begum, “Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase”, Proceedings of the National Academy of Sciences (PNAS), 2014, 111, E1016. [https://doi.org/10.1073/pnas.1402391111], [IF: 11.2].
    • D. Ghosh, A. K. Pradhan, S. Mondal, N. A. Begum, D. Mandal*, “Proton transfer reactions of 4′-chloro substituted 3-hydroxyflavone in solvents and aqueous micelle solutions”, Phys Chem Chem Phys, 2014, 16, 8594. [https://doi.org/10.1039/C3CP52209A], [IF: 3.676].
    • S. Mondal*, S. Basu, N. A. Begum, D. Mondal, “A Brief Introduction to the Development of Biogenic Synthesis of Metal Nanoparticles”, Journal of Nano Research, 2014, 27, 41. [https://doi.org/10.4028/www.scientific.net/JNanoR.27.41], [IF: 1.238].
    • N. Roy, Md N. Alam, S. Mondal, I. Sk, R. A. Laskar, S. Das, D. Mandal, N. A. Begum, “Exploring Indian Rosewood as a promising biogenic tool for the synthesis of metal nanoparticles with tailor-made morphologies”, Process Biochemistry, 2012, 47, 1371. [https://doi.org/10.1016/j.procbio.2012.05.009], [IF: 3.757].
    • S. Mondal, N. Roy, R.A. Laskar, S. Basu, D. Mandal, N. A. Begum*, “Biogenic synthesis of Au, Ag and bimetallic Au/Ag nanopaticles using Mahogany (Swietenia mahogany JACQ.) leaf extract”, Colloids and Surfaces B: Biointerfaces, 2011, 82, 497. [https://doi.org/10.1016/j.colsurfb.2010.10.007], [IF: 5.268].
    • S. Basu, S. Mondal, D. Mandal*, “Proton transfer reactions in nanoscopic polar domains: 3-Hydroxyflavone in AOT reverse micelles”, Journal of Chemical Physics, 2010, 132, 034701. [https://doi.org/10.1063/1.3272526], [IF: 3.48].
    • N. Roy, S. Mondal, R.A. Laskar, S. Basu, D. Mandal, N. A. Begum*, “Biogenic synthesis of Au and Ag Nanoparticles by Indian Propolis and its Constituents”, Colloids and Surfaces B: Biointerfaces, 2010, 76, 317. [https://doi.org/10.1016/j.colsurfb.2009.11.011], [IF: 5.268].
    • S. Basu, S. Mondal, D. Mandal*, “3, 3'-diethyloxacarbocyanine iodide: a new microviscosity probe for micelles and microemulsions”, Colloids and Surfaces A: Phys. Engg. Aspects, 2010, 363, 41. [https://doi.org/10.1016/j.colsurfa.2010.04.011], [IF: 4.539].
    • S. Mondal, S. Basu, D. Mandal*, “Ground- and excited-state proton-transfer reaction of 3-Hydroxyflavone in aqueous Micelles” Chemical Physics Letters, 2009, 479, 218. [https://doi.org/10.1016/j.cplett.2009.08.026], [IF: 2.328].
    • N.A. Begum, S. Mondal, S. Basu, R.A. Laskar, D. Mandal*, “Biogenic synthesis of Au and Ag nanoparticles using aqueous solutions of Black Tea leaf extracts”, Colloids and Surfaces B: Biointerfaces, 2009, 71, 113. [https://doi.org/10.1016/j.colsurfb.2009.01.012], [IF: 5.268].
    • N.A. Begum, N. Roy, S. Mandal, S. Basu, D. Mandal*, “Fluorescence Spectroscopy of a Naturally Occurring Carbazole Alkaloid: Murrayanine”, Journal of Luminescence, 2009, 129, 158. [https://doi.org/10.1016/j.jlumin.2008.09.005], [IF: 3.599].
    • S. Basu, S. Mondal, U.Chatterjee, D. Mandal*, “Poly (styrene-b-2-(N,N-dimethylamino)ethyl methacrylate) Diblock Copolymers: Micellization   and Application in the Synthesis of Photoluminescent CdS Nanoparticles”, Materials  Chemistry and Physics, 2009, 116, 578. [https://doi.org/10.1016/j.matchemphys.2009.04.040], [IF: 4.094].
    • S. Basu, D. P. Chatterjee, U. Chatterjee, S. Mondal, D. Mandal*, “Fluorescence probing of block copolymeric micelles using Coumarin 153”, Colloids and Surfaces A: Phys. Engg. Aspects, 2009, 341, 13. [https://doi.org/10.1016/j.colsurfa.2009.03.022], [IF: 4.539].

 

    • Application of Quantum Dots in Biology and Medicine: Recent Advances, Editor(s): Dr. S. Mondal & Dr. P. Barik, Springer Nature, ISBN: 978-9811931437, 1st Edition, 2022.

 

OP/RC/FDP

    • 109th Orientation Programme, UGC-HRD Centre, The University of Burdwan (15/02/2018-14/03/2018)
    • Refresher Course on “Role of Biotechnology in Pharmacy”, QIP Nodal Cell (Pharmacy), Department of Pharmaceutical Technology, Jadavpur University, (17/05/2017-30/05/2017).
    • Refresher Course in Advances in Instrumentation and Automation: Role of ICT, Dept. Of Instrumentation and Electronics Engineering, Jadavpur University, Kolkata (03/12/2018-22/12/2018).
    • Online Refresher Course In Chemistry For Higher Education, SWAYAM ARPIT Course for Career Advancement Scheme (CAS) promotion (2019-2020)
    • One Week Online National Faculty Development Program on “Assessment and Evaluation in Higher Education” organized by Guru Angad Dev Teaching Learning Centre, SGTB Khalsa College, University of Delhi under the Pandit Madan Mohan Malaviya National Mission on Teachers and Teaching (PMMMNMTT) of Ministry of Education (14/07/2021-20/07/2021).

 

      1. Invited Speaker in National Seminar on ‘“Recent Developments in Biotechnology in Human Welfare (RDBHW-2019)” JIS University, Agarpara, Kolkata (25/04/2019).
      2. Invited Speaker in “Weekly Scientific Seminar”, Chittaranjan National Cancer Institute, Ministry of Health & Family Welfare, Kolkata (04/09/2019).
 

2016-17

      1. 👉One-Day Seminar, Organized by Department of Chemistry, Rammohan College, 26/08/2016.
      2. 👉1st Regional Science and Technology Congress (Southern Region) 2016, Organized by NITTTR, Kolkata and Department of higher Education and Science and Technology and Biotechnology Government of West Bengal, 13/11/2016-14/11/2016. (Oral)
      3. 👉International symposium on immune diversity and cancer therapy Kobe 2017, Kobe biomedical innovation cluster promotion council, Kobe City, Foundation of Biomedical Research and Innovation, Kobe, Japan, 26/01/2017-28/01/2017. (Poster/Oral)
      4. 👉24th West Bengal State Science and Technology Congress 2017, Department of higher Education and Science and Technology and Biotechnology Government of West Bengal, 28/02/2017-01/03/2017. (Oral)

2017-18

      1. 👉2nd Regional Science and Technology Conress (Southern Region) 2017, Department of higher Education and Science and Technology and Biotechnology Government of West Bengal, 14/12/2017-15/12/2017. (Oral)
      2. 👉International Seminar on “Recent Trends in Macromolecular Chemistry (RTMC 2018)”, Department of Chemistry, City College, Kolkata and Indian Chemical Society, 10/01/2018. (Poster)

2018-19

      1. 👉3rd Regional Science and Technology Congress (Southern Region), 2018, Department of higher Education and Science and Technology and Biotechnology Government of West Bengal, 18/12/2018-19/12/2018. (Oral)

2019-20

      1. 👉International Seminar on “Elements of periodic table in the chemical avenues of Biological World”, Organized by Department of Chemistry and Zoology, South Calcutta Girls’ College, 17/12/2019. (Poster)
      2. 👉Two-day International Seminar on “Innovation, Expansion, Impacts and Challenges in Chemical and Biological Sciences”, Organized by Department of Chemistry, Surendranath College, 08/01/2020-09/01/2020. (Poster)
      3. 👉National Conference on “Recent development and future challenges in Chemical Science (RDFCS-2020)” Organized by Department of Chemistry, Behala College, Kolkata in collaboration with Royal Society of Chemistry, Eastern India Section, Kolkata, 26/02/2020. (Poster)

2020-21

      1. 👉Convener, National Webinar “COVID-19 pandemic: Defining new normal”, Rammohan College, Kolkata (04/07/2020).
      2. 👉A one-day International Webinar “COVID-19, the facts and findings”, Dept. of Chemistry, Sidho-Kanho-Birsha University, Purulia, West Bengal, India (08/06/2020) [Oral Presentation].
      3. 👉International Webinar “COVID-19 pandemic: challenges and recent advancements”, Jawaharlal Nehru University, New Delhi, India (25/04/2020-26/04/2020).
      4. 👉Webinar on “Steps towards life: Chemistry” by Prof. Jean Marie Lehn, Nobel Laureate, Organized by Department of Chemistry, Adamas University, Kolkata (29/05/2020).
      5. 👉Webinar on Pharmaceutical Chemistry, Semester IV, Chemistry Course, 06/06/2020.
      6. 👉National Webinar on “COVID-19: Testing and Modelling perspective”, Organized by Surendranath College, Kolkata (05/07/2020).
      7. 👉International Webinar on “Academics vs Industry: Choosing the right path”, Organized by Department of Chemistry, Surendranath College, Kolkata (06/07/2020).
      8. 👉One day National Level Webinar on “The enigma of COVID-19: Features, Genomic plasticity and treatment modalities”, Organized by Krishnagar Government College, Nadia (22/07/2020).
      9. 👉One day National Webinar “How to conduct online Teaching-learning in COVID times?”, Organized by Guru Angad Dev Teaching Learning Centre, PMMMNMTT of MHRD (22/07/2020).
      10. 👉Four-Day National Webinar on Discipline specific Elective (DSE) topics of UG Chemistry (Hons.), CBCS syllabus, University of Calcutta, jointly organized by Moulana Azad College and Asutosh College, Kolkata (04/08/2020-07/08/2020).
      11. 👉3 days International virtual workshop on “COVID-19: RT-PCR diagnostics & therapeutics”, University of Kalyani & CoM-JNM Hospital (05/08/2020-07/08/2020).
      12. 👉International Seminar on “Recent advances in Chemistry & Material Sciences-2020”, Indian Chemical Society & American Chemical Society (August 2020). (Oral)
      13. 👉International Webinar on “Chemistry and recent developments in medicinal field”, Organized by Department of Chemistry, Surendranath Evening College, Kolkata (23/08/2020).
      14. 👉Two-Day State level webinar on Skill Enhancement Courses (SEC) of UG Chemistry (Hons.), CBCS Syllabus, University of Calcutta, jointly organized by Moulana Azad College and Asutosh College, Kolkata (24/08/2020-25/08/2020).
      15. 👉Young Scientist Conference (YSC), India International Science Festival 2020 (IISF 2020), Organized by Ministry of Science and Technology, Ministry of Earth Sciences, Ministry of Health and Family Welfare, Govt. of India in collaboration with VIBHA and CSIR (22/12/2020-25/12/2020). (Oral)
      16. 👉Two day “Awareness workshop-NIRF India Rankings-2021 for Higher Educational Institutions”, Institute of Academic Excellence & Collegiate Education & Technical Education Department, Govt. of Telangana (18/01/2021-19/01/2021).
      17. 👉3 days International virtual workshop on “COVID-19: RT-PCR diagnostics & therapeutics”, University of Kalyani & CoM-JNM Hospital (05/08/2020-07/08/2020).
      18. 👉International Webinar on “DNA Topoisomerase IIB”, Organized by Asutosh College, Kolkata (04/02/2021).
Front cover of that renowned journal drawing by me.

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